Bibliographic information
GuidelineWHO guidelines for the clinical management of filovirus disease
Year of Publication2026
Issuing InstitutionWorld Health Organization
Recommendation
New
WHO suggests against the use of tranexamic acid in patients with confirmed filovirus disease and haemorrhage.
Recommended against
Conditional
Certainty of evidence
Very low
Notes and Remarks
- This recommendation applies to adults and children with filovirus disease that have bleeding from intravenous sites, gastrointestinal tract and oral mucosa. • This does not apply to patients with filovirus that are bleeding due to a condition for which tranexamic acid has a proven benefit, such as postpartum haemorrhage, surgical bleeding or trauma.